MDMA and 5-HTP (same day)
Recovery only - the next day.
Why this happens
A serotonin precursor. Taken the same day as MDMA it adds to the serotonin load. It belongs to recovery, the day after - never alongside.
What this means in practice
Best avoided. If they are combined anyway, keep doses low, watch the person closely, and be ready to call for help.
Warning signs - get help
Call your local emergency number straight away if you notice any of these:
- A high fever or skin that is hot to the touch
- Agitation, confusion or hallucinations
- Rigid, twitching or cramping muscles
- A racing heartbeat
- Heavy sweating or shivering
Information, not medical advice. Threshold does not promote or encourage MDMA use. This exists so that people who make their own choices can make safer, better-informed ones. It is not a substitute for professional care.
Sources
- Qualitative review of serotonin syndrome, ecstasy (MDMA) and the use of other serotonergic substances: hierarchy of risk - Australian & New Zealand Journal of Psychiatry (2007)